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年度
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論文
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| 2015 |
Cells of a common developmental origin regulate REM/non-REM sleep and wakefulness in mice
Yu Hayashi, Mitsuaki Kashiwagi, Kosuke Yasuda, Reiko Ando, Mika Kanuka, Kazuya Sakai, Shigeyoshi Itohara
Science 20 Nov 2015: Vol. 350, Issue 6263, pp. 957-961 DOI: 10.1126/science.aad1023
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| 2015 |
Morning and evening physical exercise differentially regulate the autonomic nervous system during nocturnal sleep in humans
Yujiro Yamanaka, Satoko Hashimoto, Nana N. Takasu, Yusuke Tanahashi, Shin-ya Nishide, Sato Honma, and Ken-ichi Honma
Am J Physiol Regul Integr Comp Physiol 309: R1112?R1121, 2015, doi:10.1152/ajpregu.00127.2015.
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| 2014 |
Differential regulation of circadian melatonin rhythm and sleep-wake cycle by bright lights and nonphotic time cues in humans
Yujiro Yamanaka, Satoko Hashimoto, Satoru Masubuchi, Akiyo Natsubori, Shin-ya Nishide, Sato Honma, and Ken-ichi Honma
Am J Physiol Regul Integr Comp Physiol 307: R546?R557, 2014, doi:10.1152/ajpregu.00087.2014.
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| 2014 |
Optogenetic Manipulation of Activity and Temporally Controlled Cell-Specific Ablation Reveal a Role for MCH Neurons in Sleep/Wake Regulation
Tomomi Tsunematsu, Takafumi Ueno, Sawako Tabuchi, Ayumu Inutsuka, Kenji F. Tanaka, Hidetoshi Hasuwa, Thomas S. Kilduff, Akira Terao, and Akihiro Yamanaka
The Journal of Neuroscience, 14 May 2014, 34(20): 6896-6909;
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| 2014 |
Conditional Ablation of Orexin/Hypocretin Neurons: A New Mouse Model for the Study of Narcolepsy and Orexin System Function
Sawako Tabuchi, Tomomi Tsunematsu, Sarah W. Black, Makoto Tominaga, Megumi Maruyama, Kazuyo Takagi, Yasuhiko Minokoshi, Takeshi Sakurai, Thomas S. Kilduff, and Akihiro Yamanaka
The Journal of Neuroscience, 7 May 2014, 34(19): 6495-6509;
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| 2014 |
Extended Wakefulness: Compromised Metabolics in and Degeneration of Locus Ceruleus Neurons
Jing Zhang, Yan Zhu, Guanxia Zhan, Polina Fenik, Lori Panossian, Maxime M. Wang, Shayla Reid, David Lai, James G. Davis, Joseph A. Baur, and Sigrid Veasey
J. Neurosci., Mar 2014; 34: 4418 - 4431.
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| 2014 |
Chronic Sleep Restriction Disrupts Sleep Homeostasis and Behavioral Sensitivity to Alcohol by Reducing the Extracellular Accumulation of Adenosine
Jerome Clasadonte, Sally R. McIver, Luke I. Schmitt, Michael M. Halassa, and Philip G. Haydon
J. Neurosci., Jan 2014; 34: 1879 - 1891.
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| 2013 |
Dietary Therapy Mitigates Persistent Wake Deficits Caused by Mild Traumatic Brain Injury
Miranda M. Lim, Jaclynn Elkind, Guoxiang Xiong, Ray Galante, Jingxu Zhu, Lin Zhang, Jie Lian, Julianna Rodin, Nicholas N. Kuzma, Allan I. Pack, and Akiva S. Cohen
Science Translational Medicine, Dec 2013; 5: 215ra173.
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| 2013 |
Optogenetic Stimulation of MCH Neurons Increases Sleep Roda Rani Konadhode, Dheeraj Pelluru, Carlos Blanco-Centurion, Andrew
Zayachkivsky, Meng Liu, Thomas Uhde, W. Bailey Glen, Jr, Anthony N. van den Pol, Patrick J. Mulholland, and Priyattam J. Shiromani
J. Neurosci., Jun 2013; 33: 10257 - 10263.
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| 2013 |
Role of the Medial Prefrontal Cortex in Cataplexy
Yo Oishi, Rhiannan H. Williams, Lindsay Agostinelli, Elda Arrigoni, Patrick M. Fuller, Takatoshi Mochizuki, Clifford B. Saper, and Thomas E. Scammell
J. Neurosci., Jun 2013; 33: 9743 - 9751.
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| 2013 |
Auditory Responses and Stimulus-Specific Adaptation in Rat Auditory Cortex are Preserved Across NREM and REM Sleep
Yuval Nir, Vladyslav V. Vyazovskiy, Chiara Cirelli, Matthew I. Banks, and Giulio Tononi
Cereb Cortex, Dec 2013; 10.1093/cercor/bht328
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| 2013 |
Extracellular Signal-Regulated Kinase (ERK) Activity During Sleep Consolidates Cortical Plasticity In Vivo
Michelle C. Dumoulin, Sara J. Aton, Adam J. Watson, Leslie Renouard, Tammi Coleman, and Marcos G. Frank
Cereb Cortex, Sep 2013; 10.1093/cercor/bht250.
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| 2013 |
Amygdala Lesions Reduce Cataplexy in Orexin Knock-Out Mice
Christian R. Burgess, Yo Oishi, Takatoshi Mochizuki, John H. Peever, and Thomas E. Scammell
J. Neurosci., Jun 2013; 33: 9734 - 9742
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| 2013 |
Sleep spindles are generated in the absence of T-type calcium channel-mediated low-threshold burst firing of thalamocortical neurons
Jungryun Lee, Kiyeong Song, Kyoobin Lee, Joohyeon Hong, Hyojung Lee, Sangmi Chae, Eunji Cheong, and Hee-Sup Shin
PNAS, Dec 2013; 110: 20266 - 20271.
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| 2013 |
Astrocyte control of synaptic NMDA receptors contributes to the progressive development of temporal lobe epilepsy
Jerome Clasadonte, Jinghui Dong, Dustin J. Hines, and Philip G. Haydon
PNAS, Oct 2013; 110: 17540 - 17545
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| 2013 |
Effects of Sleep and Wake on Oligodendrocytes and Their Precursors
Michele Bellesi, Martha Pfister-Genskow, Stephanie Maret, Sunduz Keles, Giulio Tononi, and Chiara Cirelli
J. Neurosci., Sep 2013; 33: 14288 - 14300.
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| 2013 |
Sleep Stage Assessment Using Power Spectral Indices of Heart Rate Variability With a Simple Algorithm: Limitations Clarified From Preliminary Study
Keiko Tanida, Masashi Shibata, and Margaret M. Heitkemper
Biol Res Nurs, Jul 2013; 15: 264 - 272.
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| 2013 |
Progressive sleep and electroencephalogram changes in mice carrying the Huntington’s disease mutation
Sandor Kantor, Lajos Szabo, Janos Varga, Marc Cuesta, and A. Jennifer Morton
Brain, Jul 2013; 136: 2147 - 2158.
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| 2013 |
Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation
Jasbir Dalal, Jee Hoon Roh, Susan E. Maloney, Afua Akuffo, Samir Shah, Han Yuan, Brie Wamsley, Wendell B. Jones, Cristina de Guzman Strong, Paul A. Gray, David M. Holtzman, Nathaniel Heintz, and Joseph D. Dougherty
Genes and Dev., Mar 2013; 27: 565 - 578.
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| 2009 |
Feeding-elicited cataplexy in orexin knockout mice.
E. L. CLARK,a C. R. BAUMANN,a,b G. CANO,a T. E. SCAMMELLa AND T. MOCHIZUKI
Neuroscience 161 (2009) 970.977
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| 2009 |
Effects of some antipsychotics and a benzodiazepine hypnotic on the sleep-wake pattern in an animal model of schizophrenia.
Ishida,T,Obara Y, Kamei C
J Pharmacol Sci. 2009 Sep;111(1):44-52. Epub 2009 Aug 29
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| 2008 |
Neural circuitry of stress-induced insomnia in rats.
Georgina Cano, Takatoshi Mochizuki, and Clifford B. Saper
The Journal of Neuroscience, October 1, 2008 . 28(40):10167.10184 . 10167
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| 2008 |
Studies on somnolence in the daytime caused by drugs used for neuropathic pain.
Takeda Y, Ishida T, Tsutsui R, Toide K, Tanimoto-Mori S, Watanabe S, Kanai Y, Kamei C.
J Pharmacol Sci. 2008 Jul;107(3):246-50. Epub 2008 Jun 28.
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| 2008 |
Algorithm for sleep scoring in experimental animals based on fast Fourier transform power spectrum analysis of the electroencephalogram
Sayaka KOHTOH, Yujiro TAGUCHI, Naomi MATSUMOTO, Masashi WADA, Zhi-Li HUANG andYoshihiro URADE
Sleep and Biological Rhythms Volume 6, Issue 3, pages 163?171, July 2008
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| 2008 |
Effects of Ibotenate and 192IgG-Saporin Lesions of the Nucleus Basalis Magnocellularis/Substantia Innominate on Spontaneous Sleep and Wake States and on Recovery Sleep after Sleep Deprivation in Rats
SembaSatvinder Kaur, Adrienne Junek, Michelle A. Black, and Kazue Semba
J. Neurosci., Jan 2008; 28: 491-504
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| 2007 |
Selective Blockade of 5-Hydroxytryptamine (5-HT)7 Receptors Enhances 5-HT Transmission, Antidepressant-Like Behavior, and Rapid Eye Movement Sleep Suppression Induced by Citalopram in Rodents
Pascal Bonaventure, Lisa Kelly, Leah Aluisio, Jonathan Shelton, Brian Lord, Ruggero Galici, Kirsten Miller, John Atack, Timothy W. Lovenberg, and Christine Dugovic
J. Pharmacol. Exp. Ther., May 2007; 321: 690 - 698.
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| 2007 |
Altered Circadian and Homeostatic Sleep Regulation in Prokineticin 2-Deficient Mice
Wang-Ping Hu,PhD1; Jia-Da Li, PhD1; Chengkang Zhang, PhD1; Lisa Boehmer, PhD2; Jerome M. Siegel, PhD2; Qun-Yong Zhou, PhD1
SLEEP, Vol. 30, No. 3, 2007
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| 2007 |
Extract of Ganoderma lucidum potentiates pentobarbital-induced sleep via a GABAergic mechanism
Qing-Ping Chu, Li-En Wang, Xiang-Yu Cui, Hong-Zheng Fu, Zhi-Bin Lin, Shu-Qian Lin, Yong-He Zhang
Pharmacology Biochemistry and Behavior, Volume 86, Issue 4, April 2007, Pages 693-698
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| 2007 |
Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy
Shengwen Zhang, Jamie M. Zeitzer, Takeshi Sakurai, Seiji Nishino, and Emmanuel Mignot
J. Physiol., Jun 2007; 581: 649 - 663.
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| 2006 |
Catecholamine neurones in rats modulate sleep, breathing, central chemoreception and breathing variability
Aihua Li and Eugene Nattie
J. Physiol., Jan 2006; 570: 385 - 396.
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| 2006 |
Altered sleep.wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice
Zhi-Li Huang, Takatoshi Mochizuki, Wei-Min Qu, Zong-Yuan Hong, Takeshi Watanabe, Yoshihiro Urade, and Osamu Hayaishi
PNAS, Mar 2006; 103: 4687 - 4692.
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| 2006 |
Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep
Wei-Min Qu, Zhi-Li Huang, Xin-Hong Xu, Kosuke Aritake, Naomi Eguchi, Fumio Nambu, Shu Narumiya, Yoshihiro Urade, and Osamu Hayaishi
PNAS, Nov 2006; 103: 17949 - 17954.
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| 2006 |
Attenuated Circadian Rhythms in Mice Lacking the Prokineticin 2 Gene
Jia-Da Li, Wang-Ping Hu, Lisa Boehmer, Michelle Y. Cheng, Alex G. Lee, Alexander Jilek, Jerome M. Siegel, and Qun-Yong Zhou
J. Neurosci., Nov 2006; 26: 11615 - 11623.
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| 2005 |
Excitatory and Inhibitory Actions of Isoflurane in Cholinergic Ascending Arousal System of the Rat
Hailong Dong, M.D., Ph.D., Satoru Fukuda, M.D., Ph.D., Tetsuro Isada, M.D., Hirotake Eguchi, M.D., Hisato Suzuki, M.D.
Anesthesiology 2005; 103: A155
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| 2005 |
Effects of kava-kava extract on the sleep-wake cycle in sleep-disturbed rat s
Shinomiya K, Inoue T, Utsu Y, Tokunaga S, Masuoka T, Ohmori A, Kamei C.
Psychopharmacology (Berl) 2005 Feb 8
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| 2005 |
Effects of Valerian Extract on the Sleep-wake Cycle in Sleep-disturbed Rats
Kazuaki Shinomiya, Katsuyuki Fujimura, Yonsu Kim, and Chiaki Kamei
Acta Med Okayama. 2005 Jun;59(3):89-92.
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| 2005 |
An adenosine A2A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats
Zong-Yuan Hong, Zhi-Li Huang, Wei-Min Qu, Naomi Eguchi, Yoshihiro Urade and Osamu Hayaishi
Journal of Neurochemistry Volume 92 Issue 6 Page 1542 - March 2005 doi:10.1111/j.1471-4159.2004.02991.x
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| 2005 |
Despite Similar Anxiolytic Potential, the 5-Hydroxytryptamine 2C Receptor Antagonist SB-242084 [6-Chloro-5-methyl-1-[2-(2-methylpyrid-3-yloxy)-pyrid-5-yl Carbamoyl] Indoline] and Chlordiazepoxide Produced Differential Effects on Electroencephalogram Power Spectra
Sandor Kantor, Rita Jakus, Eszter Molnar, Norbert Gyongyosi, Attila Toth, Laszlo Detari, and Gyorgy Bagdy
Journal of Pharmacology And Experimental Therapeutics Fast Forward First published on August 5, 2005; DOI: 10.1124/jpet.105.086413
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| 2005 |
COMPARATIVE EFFECT OF MELATONIN AND ZOLPIDEM ON SLEEP USING RADIOTELEMETRY IN RATS
ZSimon P Fisher, Kathryn Davidson, and David Sugden
European Pineal and Biological Rhythms Society 2005 Poster presentation
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| 2005 |
Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine.
Zhi-Li Huang, Wei-Min Qu, Naomi Eguchi, Jiang-Fan Chen, Michael A Schwarzschild, Berti B Fredholm, Yoshihiro Urade and Osamu Hayaishi
Nature Neuroscience, Published online: 19 June 2005; doi: 10, 1038/nn1491
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| 2004 |
Extracellular histamine level in the frontal cortex is positively correlated with the amount of wakefulness in rats
Min Chua, Zhi-Li Huanga, Wei-Min Qu, Naomi Eguchi, Ming-Hui Yao, Yoshihiro Urade
Neuroscience Research 49 (2004) 417.420
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| 2004 |
Accuracy evaluation of sleep-wake stage analysis with SleepSign Ver2.0
Yujiro TAGUCHI, Shima HANDO, Mie SAKATA, Naomi EGUCHI and Yoshihiro URADE
Sleep and Biological Rhythms Volume 2 Issues1Page S58 - May 2004 doi:10.1111/j.1479-8425.2004.00117.x
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| 2004 |
Effects of a single dose of 3,4-methylenedioxymethamphetamine on circadian patterns, motor activity and sleep in drug-naive rats and rats previously exposed to MDMA
Brigitta Balogh, Eszter Molnar, Rita Jakus, Linda Quate, Henry J. Olverman, Paul A. T. Kelly, Sandor Kantor and Gyorgy Bagdy
Psychopharmacology (Berl). 2004 May;173(3-4):296-309. Epub 2004 Apr 9
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| 2004 |
Increased wakefulness, motor activity and decreased theta activity after blockade of the 5-HT2B receptor by the subtype-selective antagonist
Kantor S, Jakus R, Balogh B, Benko A, Bagdy G.
Br J Pharmacol. 2004 Aug;142(8):1332-42. Epub 2004 Jul 20.
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| 2004 |
Thalamic Cav3.1 T-type Ca2_ channel plays a crucial role in stabilizing sleep
Matthew P. Anderson, Takatoshi Mochizuki, Jinghui Xie, Walter Fischler, Jules P. Manger, Edmund M. Talley, Thomas E. Scammell, and Susumu Tonegawa
www.pnas.org/cgi/doi/10.1073/pnas.0409644102, December, 2004
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| 2004 |
Expression of a Poly-Glutamine-Ataxin-3 Transgene in Orexin Neurons Induces Narcolepsy.Cataplexy in the Rat
Carsten T. Beuckmann, Christopher M. Sinton, S. Clay Williams, James A. Richardson, Robert E. Hammer, Takeshi Sakurai, and Masashi Yanagisawa
The Journal of Neuroscience, May 5, 2004, 24(18):4469-4477
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| 2004 |
Sleep Deprivation and Cellular Responses to Oxidative Stress
Anupama Gopalakrishnan, PhD; Li Li Ji, PhD; Chiara Cirelli MD, PhD
Sleep. 2004 Feb 1;27(1):27-35.
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| 2004 |
Lack of delta waves and sleep disturbances during non-rapid eye movement sleep in mice lacking 1G-subunit of T-type calcium channels
Jungryun Lee, Daesoo Kim, and Hee-Sup Shin
PNAS | December 28, 2004 | vol. 101 | no. 52 | 18195-18199
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| 2004 |
SLEEP/WAKE PATTERNS IN MICE LACKING FATTY ACID AMIDE HYDROLASE
S.Huitron-Resendiz; M.Sanchez-Alavez; D.N.Wills; B.F.Cravatt; S.J.Henriksen
Soceity for Neuroscience 2004 Poster presentation
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| 2004 |
Effects of three hypnotics on the sleep-wakefulness cycle in sleep-disturbed rats.
Shinomiya K, Shigemoto Y, Omichi J, Utsu Y, Mio M, Kamei C.
Psychopharmacology (Berl). 2004 Apr;173(1-2):203-9. Epub 2004 Jan 14.
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| 2003 |
Minireview: Sleep regulation in adenosine A2A receptor-deficient mice
Yoshihiro Urade, Naomi Eguchi, Wei-Min Qu, Mie Sakata, Zhi-Li Huang, Jiang-Fan Chen, Michael A. Schwarzschild, J. Stephen Fink, and Osamu Hayaishi
Neurology, Vol. 61, Issue 90116, S -96, December 9, 2003
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| 2003 |
Characterization Of The Sleep Patterns Of Fatty Acid Amide Hydrolase Knockout Mice
Huitron-Resendiz S, Gallegos RA, Wills DN, Zhukov VI, Cravatt BF,Henriksen SJ
Journal Sleep 2003 Abstracts
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| 2003 |
Prostaglandin E2 Activates the Histaminergic System via the EP4 Receptor to Induce Wakefulness in Rats
Zhi-Li Huang, Yo Sato, Takatoshi Mochizuki, Tetsuya Okada, Wei-Min Qu, Atsushi Yamatodani, Yoshihiro Urade, and Osamu Hayaishi
The Journal of Neuroscience,July 9, 2003, 23(14):5975-5983
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| 2002 |
AUTOMATIC VIGILANCE STATE CLASSIFICATION OF RATS AND MICE USING COMMERCIAL SLEEP ANALYSIS SOFTWARE
Gallegos RA, Huitron-Resendiz S, Sanchez-Alavez M, CriadoJR, Wills DN, Henriksen SJ
Journal Sleep 2002 Abstracts
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| 2001 |
Arousal effect of orexin A depends on activation of the histaminergic system
Zhi-Li Huang, Wei-Min Qu, Wei-Dong Li, Takatoshi Mochizuki, Naomi Eguchi, Takeshi Watanabe, Yoshihiro Urade, and Osamu Hayaishi
PNAS | August 14, 2001 | vol. 98 | no. 17 | 9965-9970
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| 2001 |
Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep
Akira Mizoguchi, Naomi Eguchi, Kazushi Kimura, Yoshimoto Kiyohara, Wei-Min Qu, Zhi-Li Huang, Takatoshi Mochizuki, MichaelLazarus, Takuya Kobayashi, Takeshi Kaneko, Shuh Narumiya, Yoshihiro Urade, and Osamu Hayaishi
Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11674-9. Epub 2001 Sep 18.
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